Six major powers are due to meet in New York later ton Saturday to consider a response to Iran's nuclear defiance. Britain, France, Germany, Russia and the United States are sending top officials of their respective foreign ministries at the meeting hosted by the European Union. <br/><br/>The six officials representing the so-called P5+1 are scheduled to meet at the EU mission in New York, but a diplomat cautioned against expecting any spectacular outcome. A senior security adviser representing the EU, Robert Cooper, will brief reporters at the end of the closed-door meeting. US Secretary of State Hillary Clinton announced on Monday that the six would explore the kind and degree of sanctions that should be pursuing as Iran doggedly refused to comply with UN demands to halt uranium enrichment.