Three United Nations agencies have issued an urgent appeal for the Saudi-led coalition fighting in Yemen to fully lift its blockade of the country. <br/>The World Health Programme, World Food Programme and UNICEF said the closure of rebel-held ports is making an already catastrophic situation far worse. <br/><br/>The agencies warned that without fresh supplies, untold thousands would die as the government controlled ports lacked the capacity required for the volumes of commercial and humanitarian cargo previously handled by Hudaydah and Saleef, and that supplies in the country were running dangerously low. <br/><br/>Yemen is also battling one of the world's worst outbreaks of cholera, that has left nearly one million people ill and killed 2,200 people.<br/><br/>Meanwhile, UN spokesman,Stephane Dujarric said, Secretary General Antonio Guterres is very much disappointed that the Saudi-led coalition is refusing to lift its blockade of Yemen . <br/><br/>He said Guterres wrote to the Saudi ambassador to ask for an end to the blockade and to reopen the key ports of Hodeida and Saleef in rebel-held territory. <br/><br/>The coalition, which is supporting the Yemeni government in its war with the rebel Houthi movement, tightened its two-year blockade of Yemen's borders on 6th of this month in response to a ballistic missile attack on the Saudi capital Riyadh.