Commerce Minister Mr Anand Sharma will hold crucial talks on Wednesday with US Trade Representative Mr Ron Kirk on Doha round negotiations for opening up the global trade.An official release said the two leaders would also hold preparatory discussions on the US-India Trade Policy Forum scheduled to be held in New Delhi on October 26.The Doha round negotiations were stalled in July last year following sharp differences over farm subsidy between the developing nations like India and the developed economies like America.