The BSE benchmark Sensex which lost 69.92 points on Tuesday trade moved down further by 19 points, or 0.10 per cent, to 18,725 in opening trade today. Shares of state-run oil firms, banking, power and healthcare companies remained under pressure.Similarly, the wide-based National Stock Exchange Nifty index shed 11 points, or 0.20 per cent, to 5,262.In the Asian region, Hong Kong's Hang Seng index was trading 0.32 per cent lower, while Japan's Nikkei was up marginally by 0.31 per cent cent this morning. In the US, the Dow Jones Industrial Average ended 0.10 per cent lower in yesterday's trade.