The Sensex at the Bombay Stock Exchange, which lost nearly 205 points in opening trade, lost further ground and was trading 255 points in the negative territory at 16,106 when reports last came in. The 30-share had lost 738 points in the previous two sessions.All the sectoral indices, led by metal, realty, banking and auto stocks, were in the red, dragging the Sensex near the crucial 16,000 points mark. In a similar fashion, the wide-based National Stock Exchange Nifty index was trading 74 points in the red at 4,849.Brokers attributed the widespread losses to continued selling by funds and retail investors, triggered by a weakening trend on other Asian bourses following overnight losses in the US and European markets as prospects of a global recession continued to unnerve investors.In the Asian region, Japan's Nikkei index was trading 2.07 per cent lower, while Hong Kong's Hang Seng Index ended 1.83 per cent lower in early trade today. The US Dow Jones Industrial Average closed 3.51 per cent lower on Thursday.