India were today dealt a massive blow ahead of next month's ODI series against South Africa with aggressive opener Virender Sehwag ruled out due to a shoulder injury. Sehwag, who had nursed a shoulder injury a few months ago as well, will be replaced by Rohit Sharma in the squad for the five-match series starting here on January 12. BCCI said this in a statement.Board Secretary N Srinivasan added that Murali Vijay will stay back in South Africa for the ODI series, as the 17th playing member of the squad.India is currently playing a three-Test series against the Proteas, which is locked 1-1 after the visitors notched up an 87 run win in the second Test on Wednesday.The Third Test will be played from January 2 in Cape Town.