The rupee appreciated by 6 paise to 49.15 rupees per US dollar in the opening trade today on the Interbank Foreign Exchange on increased foreign capital inflows. Dealers said higher opening in local equities and gains in other Asian currencies overseas against the US dollar, supported the rupee.Thursday, the rupee had lost 20 paise to close at 49.21 against the dollar on fresh demand for the US currency from importers and fall in equity markets.