In a big blow to India's medal hopes at the London Olympics, Sania Mirza crashed out of the women doubles event of the French Open with a first round defeat along with her partner Bethanie Mattek-Sands. Sania, who is world number 10 in the individual doubles ranking, needed to stay in top-10 before the June 11 cut-off mark to make a direct entry into the women's doubles draw of the Olympics. But after today's 3-6, 6-4, 5-7 upset defeat against Nina Bratchikova of Russia and Edina Gallovits-Hall of Romania it will be quite difficult for Sania to stay in the top-10 bracket.