In US Open Tennis, the fourth and final Grand Slam of the season, defending champion Angelique Kerber has made a shocking first round exit. The world number six was stunned by the unseeded Japanese Naomi Osaka, in straight sets, 3-6, 1-6. With this, the Women's Singles section will, this time, have a new champion. Two-time winner Venus Williams, world number one Karolina Pliskova, Angelique Kerber and Maria Sharapova, who made a return after the drug ban, are being seen as the favourites.In Men's Singles, this year's Wimbledon and Australian Open winner Roger Federer averted a major upset as he edged past American Frances Tiafoe, in a five-setter, in the first round. Newly crowned world number one Rafael Nadal, however, sailed into the second round with a straight set win over Serb Dusan Lajovic.Sania Mirza, Leander Paes, Rohan Bopanna and other Indian players will begin their Doubles campaigns tomorrow.