Venus Williams of America lost 6-2, 4-6, 4-6, to Russian Ekaterina Makarova in Women Single's on the first day of the Australian Open Tennis at Melbourne today. The 33-year-old Williams, the second-oldest player in the tournament and seven-time Grand Slam singles champion, has struggled with injuries and illness in recent seasons but reached the final of the WTA event at Auckland, New Zealand, to open the year. Makarova will meet another American in the second round after qualifier Irina Falconi beat Anabel Medina Garrigues of Spain, 6-3, 6-1.Two-time finalist Li Na defeated Ana Konjuh of Croatia – the youngest player in the tournament – 6-2, 6-0 in the first round to set up a meeting with another 16-year-old in the next after Belinda Bencic of Switzerland knocked out Japanese veteran Kimiko Date-Krumm in three sets.In Men Single's, Eighth-seeded Swiss player Stanislas Wawrinka was the first player through to the second round, advancing after just 15 games when Andrey Golubev retired with an injured left leg. Wawrinka was leading 6-4, 6-1 when his Kazakh rival quit after 65 minutes. Other men advancing to the second round included Russian Mikhail Youzhny, Croatian Ivan Dodig and American Sam Querrey.India's Somdev Devvarman is the only Indian in the Singles and will play his opening match later in the tournament. The Doubles section is featuring Leander Paes, Mahesh Bhupathi, Rohan Bopanna, Divij Sharan, Yuki Bhambri and Sania Mirza with their respective team-mates.