In a major breakthrough, scientists have discovered an antibody that could minimise the internal bleeding seen in traumas like bullet wounds and car crashes. According to scientists at Oklahoma Medical Research Foundation (OMRF), they have found a specific type of antibody that can block the ability of histone, a protein which is responsible for much of the damage. <br/>It had been observed that patients with auto-immune diseases make antibodies to the proteins in their cell nuclei but it was not known why. This antibody came from a mouse with an auto-immune disease. The researchers found that when mice had a bad blood stream infection or sepsis, their blood contained high levels of histones. They checked this in primates and humans and found the same result. The OMRF team has tested the antibody in mice with sepsis and it does stop the toxic effects of the histones and they recover.<br/>They now want to test it in primates and eventually humans.<br/>